Showing posts with label longevity. Show all posts
Showing posts with label longevity. Show all posts

Monday, November 26, 2012

Dan Buettner: "Blue Zones: Second Edition"


From NPR's The Diane Rehm Show, this is a very cool discussion about "blue zones," the five places on the Earth where people tend to live significantly longer than the rest of us. Her (actually Susan Page is sitting in for Diane) guest is Dan Buettner, author of The Blue Zones, Second Edition: 9 Lessons for Living Longer From the People Who've Lived the Longest.  

One of the very cool stories is of a Greek immigrant to the U.S. who is diagnosed with terminal lung cancer at age 60 and decides to return to his home island of Ikaria to die among his people, except that he didn't. He went home, spent time with friends and family, returned to his church, consumed the local diet heavy on vegetables, fish, and red wine, and even began growing his own grapes and making his own wine - he is now 97 years old. Here is his story from the New York Times Magazine:
Moraitis [in the picture above] considered staying in America and seeking aggressive cancer treatment at a local hospital. That way, he could also be close to his adult children. But he decided instead to return to Ikaria, where he could be buried with his ancestors in a cemetery shaded by oak trees that overlooked the Aegean Sea. He figured a funeral in the United States would cost thousands, a traditional Ikarian one only $200, leaving more of his retirement savings for his wife, Elpiniki. Moraitis and Elpiniki moved in with his elderly parents, into a tiny, whitewashed house on two acres of stepped vineyards near Evdilos, on the north side of Ikaria. At first, he spent his days in bed, as his mother and wife tended to him. He reconnected with his faith. On Sunday mornings, he hobbled up the hill to a tiny Greek Orthodox chapel where his grandfather once served as a priest. When his childhood friends discovered that he had moved back, they started showing up every afternoon. They’d talk for hours, an activity that invariably involved a bottle or two of locally produced wine. I might as well die happy, he thought.

In the ensuing months, something strange happened. He says he started to feel stronger. One day, feeling ambitious, he planted some vegetables in the garden. He didn’t expect to live to harvest them, but he enjoyed being in the sunshine, breathing the ocean air. Elpiniki could enjoy the fresh vegetables after he was gone.

Six months came and went. Moraitis didn’t die. Instead, he reaped his garden and, feeling emboldened, cleaned up the family vineyard as well. Easing himself into the island routine, he woke up when he felt like it, worked in the vineyards until midafternoon, made himself lunch and then took a long nap. In the evenings, he often walked to the local tavern, where he played dominoes past midnight. The years passed. His health continued to improve. He added a couple of rooms to his parents’ home so his children could visit. He built up the vineyard until it produced 400 gallons of wine a year. Today, three and a half decades later, he’s 97 years old — according to an official document he disputes; he says he’s 102 — and cancer-free. He never went through chemotherapy, took drugs or sought therapy of any sort. All he did was move home to Ikaria.
 Read the whole article - it's a great story.


Dan Buettner: "Blue Zones: Second Edition"

Guest Host: Susan Page


Wednesday, November 21, 2012 


Okinawans maintain strong social connections through regular gatherings of a moai.
 - Photo credit: Blue Zones
Okinawans maintain strong social connections through regular gatherings of a moai.
Photo credit: Blue Zones
Researcher, explorer and author Dan Buettner on the latest research about so-called "Blue Zones" locales, where residents live longer than anywhere else on earth.


Human longevity is thought to be explained by a combination of genetic and environmental factors. But recent studies show that as much as 90 percent of life expectancy may be determined by habits. Several years ago, a team of National Geographic scientists identified four regions in the world where people live the longest. In these so-called “Blue Zones,” residents experience far lower rates of chronic disease than Americans do. And people who live in these zones share common habits: they eat mostly plants, are spiritual and have strong ties with family and friends. Now, researchers have identified a fifth Blue Zone: the island of Ikaria, Greece. Author and explorer Dan Buettner on lessons for a long life from the world’s oldest people.


Guests



Dan Buettner: author, explorer, fellow, National Geographic Society.



Related Video

Dan Buettner presented "How to live to be 100+" at TED in September 2009. To find the path to long life and health, Buettner studies the world's "Blue Zones," communities whose elders live with vim and vigor to record-setting age. In his talk, he shares the nine common diet and lifestyle habits that keep them spry past age 100.

 

Read An Excerpt

Excerpt from "The Blue Zones, Second Edition: 9 Lessons for Living Longer From the People Who've Lived the Longest" by Dan Buettner. Copyright 2012 by Dan Buettner. Reprinted here by permission of National Geographic. All rights reserved.

BlueZones2E_for Diane Rehm

Wednesday, October 03, 2012

Tami Simon Speaks with Mario Martinez - Empowerment and ‘Navigating the Drift’


Sounds True founder and leader Tami Simon speaks with clinical neuropsychologist Mario Martinez about his research into how our cultural beliefs affect our health and longevity. Great stuff.

Empowerment and ‘Navigating the Drift’

Tuesday, October 2, 2012


Tami Simon speaks with Mario Martinez, a clinical neuropsychologist whose breakthrough research examines how cultural beliefs affect our health and longevity. Mario is the founder of biocognitive science, a new paradigm that examines the dynamic relationship between thoughts, culture, and the body. With Sounds True, he has recorded an audio learning course called The Mind Body Code: How the Mind Wounds and Heals the Brain. In this episode, Tami speaks with Mario about the idea that culture creates biology; how we can access the antidote to shame, abandonment, and betrayal through healing fields in the body; and the concept of “the drift”—how we can navigate chaos with uncertainty as our guide. (68 minutes)


Play
more from Mario Martinez »

Tuesday, August 28, 2012

The Problem with Life - Is it Solved by Merging with Machines?

Here are two strangely related collections of links from yesterday's Bookforum Omnivore - one on the challenges of life, and the other on the coming singularity, when we will merge with machines (thus solving many of the problems of biological life).

The problem with life

Aug 27 2012

 And the solution?


Wednesday, August 22, 2012

Do You Want To Live Forever? - Dr. Aubrey de Grey


Interesting documentary . . . . Personally, living forever would be depressing beyond comprehension. If I could maintain the health I have right now for a few more decades, however, I might not mind living well into my 100s.

I do wonder about the psychology behind the desire to life forever, or at least indefinitely. Is it a fear of death? A fear of aging and degeneration? A fear of loss? Something else . . . .


Do You Want To Live Forever?
"Do You Want To Live Forever?" is a Channel 4 Documentary following the revolutionary life-extension and immortality ideas of this somewhat eccentric scientist, Dr. Aubrey de Grey.

This show is all about the radical ideas of a Cambridge biomedical gerontologist called Aubrey de Grey who believes that, within the next 20-30 years, we could extend life indefinitely by addressing seven major factors in the aging process. He describes his work as Strategies for Engineered Negligible Senescence (SENS).


Here is some information on de Grey's ideas from his Wikipedia entry (or actually, the entry on his SENS ideas).
Strategies for Engineered Negligible Senescence (SENS) is the term coined by British biogerontologist Aubrey de Grey for the diverse range of regenerative medical therapies, either planned or currently in development [1], for the periodical repair of all age-related damage to human tissue with the ultimate purpose of maintaining a state of negligible senescence in the patient, thereby postponing age-associated disease for as long as the therapies are reapplied. [2]

The term "negligible senescence" was first used in the early 1990s by professor Caleb Finch to describe organisms such as lobsters and hydras, which do not show symptoms of aging. The term "engineered negligible senescence" first appeared in print in Aubrey de Grey's 1999 book The Mitochondrial Free Radical Theory of Aging,[3] and was later prefaced with the term "strategies" in the article Time to Talk SENS: Critiquing the Immutability of Human Aging[4] De Grey called SENS a "goal-directed rather than curiosity-driven"[5] approach to the science of aging, and "an effort to expand regenerative medicine into the territory of aging".[6] To this end, SENS identifies seven categories of "damage" and a specific regenerative medical proposal for treating each.

While many biogerontologists find it "worthy of discussion"[7][8] and SENS conferences feature important research in the field,[9][10] some contend that the alleged benefits of de Grey's programme are too speculative given the current state of technology, referring to it as "fantasy rather than science".[11][12]
Here are the seven areas he feels need to be addressed to extend our lives considerably:
By enumerating the various differences between young and old tissue identified by the science of biogerontology, a 'damage' report was drawn, which in turn formed the basis of the SENS strategy. The results fell into seven main categories of 'damage', seven alterations whose reversal would constitute negligible senescence:
  1. cell loss or atrophy (without replacement),[4][13][14]
  2. oncogenic nuclear mutations and epimutations,[15][16][17]
  3. cell senescence (Death-resistant cells),[18][19]
  4. mitochondrial mutations,[20][21]
  5. Intracellular junk or junk inside cells (lysosomal aggregates),[22][23]
  6. extracellular junk or junk outside cells (extracellular aggregates),[18][19]
  7. random extracellular cross-linking.[18][19]
For each of these areas SENS offers at least one strategy, with a research and a clinical component. The clinical component is required because in some of the proposed therapies, feasibility has already been proven, but not completely applied and approved for human trials. These strategies do not presuppose that the underlying metabolic mechanisms of aging be fully understood, only that we take into account the form senescence takes as directly observable to science, and described in scientific literature.