Saturday, July 10, 2010

Neuroscene - Antidepressants and the Placebo Effect: Is the “Chemical Imbalance” Theory Flawed?

I'm not sure I totally agree with this argument against antidepressants - it may be partially true, for some people. I don't think we yet understand the actual mechanisms of depression, but we do know that the SSRIs increase neurogenesis which, over time, may help in healing the symptoms of depression. Either way, it's good to expose the ways in which the Big Pharma companies manufacture their research results - and hide what they don't want us to see.

Antidepressants and the Placebo Effect: Is the “Chemical Imbalance” Theory Flawed?

For many years, the medical and scientific communities have largely accepted as factual the widely-held theory that clinical depression is caused by a chemical imbalance in the brain – especially with regards to the neurotransmitter serotonin. However, repeated meta-analyses of the FDA-submitted clinical trial data do not seem to support this belief. Conversely, there is significant evidence that the patient benefits of antidepressants are largely – if not completely – due to a placebo effect.

In this podcast, we speak with Dr. Irving Kirsch, professor of psychology at the University of Hull in the United Kingdom and the author of The Emperor’s New Drugs: Exploding the Antidepressant Myth. Be sure to join us as we discuss the real story behind the effectiveness of antidepressants and why they may not be the “wonder drugs” we think they are.

The hardcover of the book is available at Amazon for as little as $6 or so and less than $10 from Amazon's own store. Follow the link above.


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