Wednesday, September 02, 2009

13 Things (in science) That Really Make No Sense

Hmmm . . . . OK, for now. From New Scientist. Apparently this is actually a sequel.

13 more things that don't make sense

(Image: Loungepark / The Image Bank / Getty)

(Image: Loungepark / The Image Bank / Getty)

Strive as we might to make sense of the world, there are mysteries that still confound us.

Here are thirteen of the most perplexing. Cracking any one of them could yield profound truths.
1.

Axis of evil

(Image: WMAP / NASA)

Radiation left from the big bang is still glowing in the sky – in a mysterious and controversial pattern

2.

Dark flow

The galaxy cluster 1E 0657-56, 3.8 billion light-years away, is one of hundreds that appear to be carried along by a mysterious cosmic flow (Image: NASA / STScI / Magellan / U.Arizona / D.Clowe et al)

Something unseeable and far bigger than anything in the known universe is hauling a group of galaxies towards it at inexplicable speed

3.

Eocene hothouse

Tens of millions of years ago, the average temperature at the poles was 15 or 20 °C (Image: judywhite / Rex Features)

Tens of millions of years ago, the average temperature at the poles was 15 or 20 °C. Now let's talk about climate change

4.

Fly-by anomalies

Artist's rendition of the Rosetta probe's closest approach to Earth, during its second fly-by on 13 November this year (Image: ESA - C. Carreau)

Space probes using Earth's gravity to get a slingshot speed boost are moving faster than they should. Call in dark matter

5.

Hybrid life

These sea squirts were created when two evolutionary lineages fused (Image: Gary Bell / Taxi / Getty)

The fusion of two distinct evolutionary lines is not supposed to work – but the seas are teeming with chimeras that prove it can

6.

Morgellons disease

Morgellons disease is unpleasant and debilitating; that is, if it exists (Image: Peter Cade / Stone / Getty)

Fatigue? Do you feel insects under your skin? Seen any strange fibres sprouting from your body? Then you've got a disease that's not supposed to exist

7.

The Bloop

The Bloop signal may have been caused by Antarctic ice breaking up, but nobody knows for sure (Image: Darryl Leniuk / Photographer's Choice / Getty)

During 1997, US undersea monitoring equipment heard a series of sounds far louder than any whale song. They were never heard again

8.

Antimatter mystery

The 27-kilometre tunnel containing the Large Hadron Collider at CERN (Image: Simon Hadley / Rex Features)

The big bang should have created matter and antimatter in equal amounts – so why didn't the universe disappear in a puff of self-annihilation?

9.

The lithium problem

The universe only contains a third as much lithium as it's supposed to (Image: ImageSource / Rex)

The universe only contains a third as much lithium as it's supposed to

10

MAGIC results

(Image: R. Wagner, Max Planck Institute for Physics, Munich)

High-energy radiation from a gamma-ray burst reached Earth 4 minutes later than the lower-energy rays. That's not how Einstein said it would be

11.

The elusive monopole

(Image: flaivoloka / Stock.xchng)

Why do magnetic poles always come paired as north and south, never alone?

12.

Noise from the edge of the universe

Are dud signals from a gravitational wave detector evidence that the universe is a holographic projection? (Image: ESA)

Are dud signals from a gravitational wave detector evidence that the universe is a holographic projection?

13.

The nocebo effect

A diagnosis of terminal illness can come true, even if it's wrong (Image: Image Source / Rex)
How a diagnosis of terminal illness can come true – even if it's wrong.

Channel N - Gifted Children

From my own experience, gifted children get shafted in public school education. When we teach to the lowest common denominator (or worse), any bright child gets ignored. Bright kids get bored, sometimes get into trouble (like me), or simply are never pushed to develop their minds. I suspect that some of this has changed in the last 30+ years, at least I hope so.

This film looks at gifted kids in England.

Gifted Children

By Sandra Kiume
August 31, 2009

Child Genius 2 – Young and Gifted

This sequel to a 2005 documentary on gifted children visits several years later to report on their development. Parenting, potential, privilege, and public education. Although it’s a Channel 4 production this episode is featured on a Canadian TV site that permits international viewing; if you’re located in the UK you can watch both episodes here.


SciAm Mind - What Is It Like to Be a Baby?

Alison Gopnik rocks - saw at the consciousness conference here in Tucson in 2008. She presented a view of children so different from what I had heard before that I was skeptical. More than a year later, I am humbled.

Here she talks to Jonah Lehrer in Mind Matters.

What Is It Like to Be a Baby?

Alison Gopnik investigates the infant mind

Alison Gopnik

Alison Gopnik is a psychologist and philosopher at the University of California, Berkeley. She's also the author of the newly released book The Philosophical Baby, which explores the inner world of young children. Mind Matters editor Jonah Lehrer chats with Gopnik about why babies might be more conscious than adults, the benefits of having an imaginary friend and why play, not necessity, is the mother of invention.

LEHRER: What first drew you to study the baby mind? As you point out in The Philosophical Baby, there's a longstanding assumption that babies are mostly mindless little people, concerned solely with their physical needs.

GOPNIK: There were three currents that converged in my own life. I’m the oldest of six children and I had my own first baby when I was 23. So I’ve always been interested in babies, and I had lots of opportunities to watch them. If you look at babies casually, as most philosophers and psychologists did for 2500 years, you don’t see much. But if you look at them carefully, as generations of mothers did, and as the great psychologist Jean Piaget did, you begin to suspect that there is much more going on. The trouble is that caregivers didn’t have the scientific evidence to back up those intuitions, and even Piaget was constrained by the limited methods that were available 70 years ago. If you just observe and interview children you’ll still miss a lot.

Then I became a philosopher and got interested in some of the big deep classical philosophical problems, especially the problem of how we come to know about the world around us. And I began to wonder whether babies and children might hold some of the answers. Putting together philosophy and children would have been difficult for most of history. But very fortunately for me, when I started graduate school there was a real scientific revolution taking place in developmental psychology. New video-recording technology meant that for the first time we could take those natural observations of children and turn them into a real science. And it became clear that that science could start to answer some of those deep philosophical questions about the human mind.

LEHRER: You provocatively argue that, in some respects, babies might be more conscious than adults. Could you explain?

GOPNIK: The conventional wisdom has been that babies must be somehow less conscious than adults, if, in fact, they are conscious at all. Even developmental psychologists, including me, have tended to say that the amazing thinking that we see in babies is “just unconscious”. But there has been a lot of interesting work on the neural and cognitive bases of consciousness in the last few years, and that leads to a very different picture.

As adults when we attend to something in the world we are vividly conscious of that particular thing, and we shut out the surrounding world. The classic metaphor is that attention is like a spotlight, illuminating one part of the world and leaving the rest in darkness. In fact, attending carefully to one event may actually make us less conscious of the rest of the world. We even know something about how the brain does this: connections from the prefrontal part of the brain both enhance our perception of the attended event and inhibit our perception of other events. And there is a chemical basis for this, too. When we pay attention to an event certain brain chemicals called cholinergic transmitters make a small part of the brain more flexible and “plastic”, better at learning, and simultaneously other inhibitory transmitters actually make irrelevant parts of the brain less flexible.

If you look at baby’s attention you see a related but very different picture. Babies and young children are much worse at intentionally focusing their attention than adults. Instead, they seem to pay attention to anything that’s unexpected or interesting – anything they can learn from. We say that children are bad at paying attention but we really mean that they’re bad at not paying attention – they easily get distracted by anything interesting. And young brains are much more generally “plastic”, more flexible and better at learning than adult brains. Young brains are bathed in the cholinergic transmitters that enhance attention in adults, but the inhibitory transmitters that damp consciousness down haven’t yet come on line. If you put all that together it suggests that babies consciousness is more like a lantern than a spotlight – that it illumines the entire world around them.

Finally, you can think about what adult experience is like when we put ourselves in the same position as babies. When we travel for instance, we are suddenly surrounded by an unexpected new world and, instead of just focusing on the important things, we take in lots of information at once. That actually makes us more vividly conscious of our surroundings, not less. I think that for babies, every day is like first love in Paris.

LEHRER: You begin The Philosophical Baby by investigating the purpose of pretending. How does make-believe help young children understand how the world actually works?

GOPNIK: Why do young children spend so much of their time pretending? The traditional answer was that children were confused about the difference between fantasy and reality. But more recent studies show that children know quite well that they are just pretending. Instead they seem to use their imagination the way that creative scientists do. One of the big new ideas about how babies learn is that they use what computer scientists call “Bayesian inference”. That means that you imagine lots of different possibilities and test how likely each possibility is.

When we have a theory of the world, we can not only say what the world is like now, we can also explore what would happen if the world was different. We can ask what would happen, for instance, if there was a rocket that traveled close to the speed of light. In fact, the ability to imagine these possibilities is one of the biggest advantages of understanding how the world works. Because we imagine, we can have invention and technology. Its actually play, not necessity, that is the mother of invention.

LEHRER: And what about imaginary friends? Do they serve an important psychological function?

GOPNIK: Imaginary friends are one of the weirder forms of pretend play in childhood. But the research shows that imaginary friends actually help children understand the other people around them and imagine all the many ways that people could be.

LEHRER: You eloquently write: "This remarkable ability to find the truth depends on the capacity to imagine and to love." Could you explain what you mean by that?

GOPNIK: Scientists and philosophers tend to treat knowledge, imagination and love as if they were all very separate parts of human nature. But when it comes to children all three are deeply entwined. Children learn the truth by imagining all the ways the world could be, and testing those possibilities. And children can only learn so much because adults help care for them. There is a special intense love between human children and the people who take care of them, not just mothers but also fathers and older sisters and great-uncles and baby-sitters. And that love doesn’t just provide us with emotional warmth and sustenance. It also lets human beings, as a species, understand the world and create new worlds ourselves.

Are you a scientist? Have you recently read a peer-reviewed paper that you want to write about? Then contact Mind Matters editor Jonah Lehrer, the science writer behind the blog The Frontal Cortex and the book Proust Was a Neuroscientist. His latest book is How We Decide.

Integral Evolution: An Interview with David Loye by Russ Volckmann

From the current issue of Integral Review.

Integral Evolution: An Interview with David Loye
Russ Volckmann

David Loye is one of those people that the longer you get to know them the more you begin to discover a bit of their depth and breadth of perspective and creativity in the world. His publications speak for themselves. His network with leading scientists and thinkers around the world is equally impressive.

Actually, my first contact was with David’s wife, Riane Eisler, author of the Chalice and the Blade (among other books written with and without David). Despite the fact that they live over the hill from me, I did not meet her face to face right away. Rather, I interviewed her over the telephone for the Integral Leadership Review, which I publish and edit. When I first approached her about doing the interview she suggested that I should interview David, but I did not know David Loye’s work at all. In that interview I discovered more about Riane’s work and the extent of their partnership. In fact, they are prime movers of a partnership approach to leadership that they promote through a nonprofit center and in a Master’s program at the California Institute of Integral Studies in San Francisco.

My conversation with Riane piqued my curiosity about David’s work and I bought one of his books, Darwin’s Lost Theory of Love. Here I found evidence of the extraordinary scope and depth of David’s work that made him a natural candidate for an interview. The only question was would I use it in Integral Leadership Review or in Integral Review: such is the quality of his interests and intellect.

Before doing the interview, I borrowed a copy of one of David’s earlier books. When I went to their house to pick it up I met them both. They are quite a team and I recommend their work to all.
—Russ Volckmann

Russ: David, welcome to Integral Review.

David: Thank you for having me.

Russ: I know you have a background in psychology. I’d like to hear a little bit about the nature of your background and then explore where you’ve gone from there.

David: Well, I started by going to the New School for Social Research during the evenings and got my masters and finally my doctorate. Then I had a brief time at Princeton as a visiting lecturer, after which I went on to UCLA School of Medicine as a research psychologist in the Neuropsychiatric Institute. I have a doctorate in Social Psychology, but my master’s was in pre-clinical. That’s roughly my background. I wound up primarily as a research psychologist.

Russ: And during what years did you do your degree at the New School?

David: Oh, gosh, that was back in the Stone Age.
(laughter)

David: It must have been in the fifties.

Russ: That preceded a lot of the work that was being done around more humanistic approaches to psychology.

David: Yes, my grounding was primarily in Freud and Jung, but most importantly Lewinian Field Theory.

Russ: Kurt Lewin’s work.

David: Yes. Kurt Lewin's work was the most formative thing for me. His work underlies not only social psychology but leadership training, as well.

Russ: In what ways was his work influential on you?

David: He was the first really true systems psychologist. There is no other psychology to match it. That’s the reason it’s been so influential. It wasn’t hooked into just Gestalt or Freud or anything. It was a fluid, highly visual-oriented psychology that could be applied to all kinds of social, political and economic problems, problems in marriage and so on. He was a great innovator in action research, which has always been my passion.

Russ: That underlies the field of organization development where I spent 22 years of my life, and apparently it related to work that you did as well. In what way were you involved in action research?

David: My early work was in the study of right/left, liberal/conservative differences. I did a lot of experiments. One of my basic books in that area is called The Leadership Passion: The Psychology of Ideology. That was very definitely action-oriented. Ever since, practically everything I’ve written, I’ve wound up laying the groundwork for whatever the area was that I was looking at by pulling together what attracted me to the works of others. Ever since, I’ve always written a closing chapter or appendices or something that applies it directly, as Lewin did, to solving all kinds of social and economic and political problems.

Russ: So this was an interest of yours as far back as the fifties.

David: Oh sure. My first book actually was The Healing of a Nation. It was heavily action oriented. It won top national awards and including one that earlier had been won by Gunner Myrdal for research on racism and how to eliminate it. It was the Anisfield-Wolfe award.

Russ: What was the thesis of The Healing of a Nation?

David: The Healing of a Nation didn’t come out until 1971, at the climatic years for the whole civil rights push. It preceded the anti-war movement that came along later. It was the heyday for doing something about race.

Russ: My senior paper in college in the early 1960s was about the impact of Gandhi’s
philosophy of Satyagraha on the civil rights movement in the U.S. We have some commonality there. And what would you say were the major theses or suggestion to come out of your book?

David: I dedicated the book to Kurt Lewin and to the great black sociologist W.E.B. DuBois. I did two things in it. One, I took the perspectives of DuBois and Lewin and suggested what in terms of their work could make a difference in ending racism in America. The significance of that book within my total output from then on was in the title, The Healing of a Nation. The perspective is that we are a sick nation. We must take a socialpsychiatric perspective on the healing of the nation. In it, I wrote my first “Program for a President” in which I took Lewin’s work and fitted it in with my previous experience with television of how to actually fairly quickly move us ahead on the whole thing of racial differences.

Russ: As we’re both aware in the current political campaign, the whole issue of racism has been brought to the forefront once again. What were your recommendations and how have you seen them play out?

David: My recommendations were primarily to launch what amounts to an electronic version of what became known as the Town Hall meeting, which was also hot back then. In politics it was later brought up by Ross Perot, but he didn’t do much with it. Actually, no one has done much with it. Howard Dean picked up on part of the idea by launching the first really sophisticated use of the Internet, which Obama,, of course has perfected beautifully. That is the approach I was suggesting back in the early days of television.

Russ: Of course John McCain has advocated the use of Town Hall meetings in the
presidential campaign—

David: Yes, but his Town Hall is just the old style. He’s not using the power of technology and communication to link a whole nation together.

Russ: Your recommendation preceded even the extraordinary communication capability of the Internet today.

David: I had never thought of it that way. That’s true. Oddly enough, back in that time, I sent the book to then-Vice President Mondale and he actually read it, which seldom happens when you send books to well-known figures. He wrote back that it was an interesting idea for that time, but politically unfeasible.
Read the whole interview.


Tuesday, September 01, 2009

Shambhala Sun - Books in Brief, September 2009

Always love to find new books. Shambhala Sun tends to review some god stuff that I end up buying.

Books in Brief September 2009

The Truth of Suffering and the Path of Liberation

By Chögyam Trungpa
Edited by Judith L. Lief
Shambhala Publications, 2009; 155 pp., $21.95 (cloth)

The four noble truths seem so straightforward that some students may be anxious to move on to what they perceive as meatier teachings. In this posthumous volume, however, Chögyam Trungpa reveals layers of subtlety in these foundational Buddhist teachings. Beginning with the first truth—there is suffering—Trungpa stresses the importance of recognizing our habits. We do everything we can to avoid suffering, preferring instead to pursue happiness. But, according to the second truth, this blind pursuit is the root of our pain. Trungpa Rinpoche explains in detail how thoughts become fixations, then emotions such as jealousy, and finally actions. Now that we’ve had our wake-up call, the third truth is that the cessation of suffering is possible. We all experience signs of awakening, but don’t seek such signs, he says. Instead, utilize them when they arise to develop confidence in the dharma. Finally, the fourth noble truth is the truth of the path. There are many guidelines to help students on their journey, yet each student must forge their own way.

Welcome to the Departure Lounge: Adventures in Mothering Mother

By Meg Federico
Random House, 2009; 208 pp., $25.00 (cloth)

Although it doesn’t directly talk about the four noble truths or otherwise use dharma lingo, this memoir by Buddhist Meg Federico does address impermanence, something that is clearly at the heart of Buddhism. By turns hilarious and heart wrenching, Welcome to the Departure Lounge is the story of Addie, Federico’s mother, in her final years. It begins when Addie, under the influence of martinis, takes a tumble and is taken to a hospital, where suddenly she sits bolt upright on the gurney and yells, “ I demand an autopsy!” Addie and Walter, her new (but not so spry) husband, have begun to show signs of Alzheimer’s, and it only gets worse. Highlights include Addie and Walter—forbidden by doctors to drink—conspiring to order cases of booze, and Walter using mail-order sexual aids to enable him to paw nightly (and indiscreetly) at Addie. But capers aside, the greatest strength of this book is the complex picture Federico gives us of her mother and of their ever-evolving relationship.

Freeing Tibet: 50 Years of Struggle, Resilience and Hope

By John B. Roberts II and Elizabeth A. Roberts
Amacom, 2009; 279 pp., $24.00 (cloth)

Written in an engaging, narrative style, Freeing Tibet is the story of a culture that has been struggling to survive for half a century. According to the husband and wife co-authors, the Cold War beginnings of Tibet’s struggle included a clandestine CIA propaganda campaign and the abandonment of Tibet’s freedom fighters in a Himalayan Bay of Pigs. Then, after the Nixon administration cut off funding for the Tibetans, their cause was adopted by the sixties counterculture movement and, finally, taken on by celebrities—actors, musicians, and world leaders. As you might expect, this book details some ugly and disturbing violations of human rights in Tibet, but lighter moments are provided by various colorful characters, chiefly Allen Ginsberg, who once apparently offered magic mushrooms to the Dalai Lama. Freeing Tibet is not the chronicle of a hopeless cause—au contraire. It tells how an engaged global community could liberate the Tibetans.

No Self, No Problem

By Anam Thubten
Snow Lion Publications, 2009; 134 pp., $14.95 (paper)

Author Anam Thubten, who was born in Eastern Tibet, undertook Buddhist training in the Nyingma tradition at an early age and has been teaching in the West since the 1990s. His teachings are unpretentious and sometimes outright humorous, but they also are profound. No Self, No Problem is about how to let go of our notions of ego identity in order to discover our true nature and achieve real liberation. “We are perfect as we are,” says Anam Thubten. “When we realize this, we are perfect. When we don’t realize this, we are also perfect.” There is a glossary of terms at the back of No Self, No Problem that those new to Buddhist concepts will find useful.

Belonging: A Culture of Place

By bell hooks
Routledge, 2009; 230 pp., $19.95 (paper)

At once hard-hitting and full of heart, this collection of essays explores issues of place and belonging in the broadest sense—family, land stewardship and global environmentalism, and the politics of race, gender, and class. Author bell hooks, who is a longtime contributor to the Shambhala Sun and was featured on our July 2006 cover, is from rural Kentucky, and our journey with her in Belongings is always rooted there, even when she takes us into the city, or from the past to the present and back again. Hooks’ language is rich and she leaves me aching for the bucolic hills and the lush tobacco fields of her youth, but with equal power she leaves me reeling with Confederate flags and displaced Cherokee. This is a thought-provoking read.

The Wisdom of Sustainability: Buddhist Economics for the 21st Century

By Sulak Sivaraksa
Koa Books, 2009; 102 pp., $12.50 (paper)

Thich Nhat Hanh, Aung San Suu Kyi, and various other luminaries have offered their praises for Sulak Sivaraksa and his writing. Sulak, the founder of the International Network of Engaged Buddhists and dozens of other educational and political grassroots organizations, has been nominated twice for the Nobel Peace Prize, received the Right Livelihood Award, and written more than one hundred books in Thai and English. In The Wisdom of Sustainability, Sulak suggests that globalization is imposing materialistic values on both developing and industrialized nations, and he offers alternatives to the current economic model. We already have more than enough organizations, parties, and strategies, says Sulak. Action alone, particularly political action, will not put an end to suffering and injustice. For that, he says, we need to achieve personal transformation.

Moody Cow Meditates

By Kerry Lee MacLean
Wisdom Publications, 2009; 32 pp., $15.95 (cloth)

Though this book is intended for the nine-to-twelve set, everyone can relate to Peter the Cow and his bad day. Things go wrong for Peter even before he wakes up. He has a nightmare involving a three-eyed alien, then, already cranky, he catches his sister drawing on his skateboard. Peter pulls her tail; she pushes him down the stairs; he cuts her doll’s hair off. Then the bovine parents find out about the hair and he gets in trouble. In this way, Peter’s woes continue until he is so mad that steam comes out of his ears and all the kiddie-calves have dubbed him “Moody Cow.” “We need Grandfather,” Mom says, picking up the phone. Now for the best part of the story: Grandfather is a great bull with enormous horns and meditation tips, which moody cows both on and off the page will want to try. This, I think, is MacLean’s best book to date. The illustrations are truly charming.


Buddhist Geeks - Episode 136: Enlightenment 2.0

Interesting discussion. I disagree wth researchers who think AI is close at hand - we don't even know how the human brain makes consciousness, let alone how to make a conscious machine.

Buddhist Geeks - Episode 136: Enlightenment 2.0

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This week we speak with Ben Geortzel, an artificial intelligence researcher and Zen-dabbling spiritual seeker. Ben shares with us his introduction to Zen and his on-going relationship to spiritual practice. He also explains what is meant by "strong artificial intelligence" and AGI (artificial general intelligence) and explains why he thinks a fully functioning AI may be as little as a decade away.

Finally, we explore the overlap between his work as an AI researcher and his experiences with Zen and other spiritual practices, through discussing a story he wrote entitled, "Enlightenment 2.0" about an enlightened AI being who determines that it is possible to construct a more enlightened mind, what Ben calls a "super mind", but isn't sure whether or not it is possible for us.

This is part 1 of a two-part series. Listen to part 2, Artificial Wisdom (airing next week).


Sharp Brains - Cognitive Enhancement via Pharmacology AND Neuropsychology, in The New Executive Brain

Looks like an interesting book, via Sharp Brains.

Cognitive Enhancement via Pharmacology AND Neuropsychology, in The New Executive Brain

(Editor's Note: given the growing media attention to three apparently separate worlds -cognitive enhancement via drugs, brain fitness training software, computerized neurocognitive assessments-, I found it refreshing to see our co-founder Elkhonon Goldberg introduce the topic of cognotropic drugs with an integrative perspective in the much updated new edition of his classic book, now titled The New Executive Brain - By Elkhonon Goldberg The New Executive Brain: Frontal Lobes In A Complex World. Below goes an excerpt).

For many neuropsychologists, like myself, science is a labor of love, but seeing patients is bread and butter. Traditionally, the clinical contribution of neuropsychology has been mostly diagnostic, with precious little to offer patients by way of treatment. Neuropsychology is not the only clinical discipline for years consigned to helpless voyeurism. Every discipline concerned with cognition shares this humbling predicament. A psychiatrist treating a schizophrenic patient or a depressed patient finds him- or herself in a similar position. There are ample pharmacological tools to treat the patient’s psychosis or mood, but very few to treat the patient’s cognition. Even though psychiatrists increasingly recognize that cognitive impairment is often more debilitating in their patients than psychosis or mood disorder, traditionally, very little direct effort has been aimed at improving cognition.

A neurologist treating a patient recovering from the effects of head injury does not fare much better. There are adequate means to control the patient’s seizures but not his or her cognitive changes, despite the fact that cognitive impairment is usually far more debilitating than an occasional seizure. Society has been so preoccupied with saving lives, treating hallucinations, controlling seizures, and lifting depression that cognition (memory, attention, planning, problem solving) has been largely ignored. Granted, various neuroleptics, anticonvulsants, antidepressants, sedatives, and stimulants do have an effect on cognition, but it is an ancillary effect of a drug designed to treat something else.

Alzheimer’s disease and other dementias have been society’s wake-up call. Here, in the most affluent country in the most affluent of times, human minds were succumbing to decay before human bodies, a sharp challenge to the tacit popular belief that the “body is frail but soul is forever.” This provided an impetus for the development of an entirely new class of drugs, which can be termed familially as “cognotropic.” Their primary and explicit purpose is to improve cognition.

Since medical and public preoccupation with dementia focuses on memory, most of the pharmacological efforts have been directed at improving memory. At the time of this writing, a handful of drugs known as “Alzheimer’s drugs” or “memory enhancers” have been approved by the U.S. Food and Drug Administration (FDA). In reality, both designations are somewhat misleading. The drugs in question are anticholinesterases. They are designed to inhibit an enzyme necessary for the breakdown of the neurotransmitter acetylcholine in the synapse, and thus to prolong its action after its release into the synapse. Acetylcholine is a neurotransmitter that plays an important role in memory as well as in other cognitive functions. Biochemical processes involving acetylcholine (“cholinergic transmission”) are impaired in Alzheimer’s dementia, but they are also impaired in many other disorders.

My first encounter with this class of drugs took place in the late 1970s and involved physostigmine (Antilirium), a first-generation anticholinesterase, now out of use as a cognitive enhancer. We gave it to a patient recovering from severe head injury. The problem with physostigmine was that its length of action (halflife) was so miserably short that no sustained therapeutic effect could be reasonably expected. At best, a very fleeting, short-term improvement could be hoped for. To capture this improvement, my colleagues and I designed a brief battery of neuropsychological tests, which my research assistants Bob Bilder and Carl Sirio rushed to administer with clockwork timing during carefully calculated, and very narrow, windows of opportunity. Fleeting though it was (and at times overshadowed by vicious diarrhea), subtle memory improvement was reproducibly present. This was a cause for hope that with some improvements this class of medications could someday have real clinical value.

A number of years later, tacrine (Cognex) appeared on the market, followed by donepezil (Aricept). These drugs are also anticholinesterases, but with a much longer action and a more meaningful therapeutic effect. They should not be thought of as exclusively “Alzheimer’s drugs” since their utility is not limited to Alzheimer’s disease. I have observed a significant, albeit transient, therapeutic effect of these drugs on cognition in patients with Parkinson’s disease and brain damage due to hypoxia.

. . . .

Our previous interview with Dr. Goldberg:

- On Cognitive Training and Brain Fitness Computer Programs

Read the whole excerpt.


Monday, August 31, 2009

Upaya Dharma Podcasts - Continuous Practice – Circle of the Way

As usual, thought-provoking dharma to feed the path.

Continuous Practice – Circle of the Way

Speakers: Sensei Kaz Tanahashi & Sensei Beate Genko Stolte

Senseis Kaz and Beate give the final talk of the sesshin “On Dogen’s Circle of the Way.” Kaz Sensei talks about The Way in various social and historical contexts, explaining that Dogen’s Circle of the Way is always complete, though perhaps imperfect. Sensei Beate speaks of language and the reality it creates as one of myriad possible realities. Beate reads an excerpt by David Foster Wallace about how the clearest parts of our reality are often the most difficult to see and to speak of.

Speakers: Sensei Kaz Tanahashi & Sensei Beate Genko StolteSpeakers: Sensei Kaz Tanahashi & Sensei Beate Genko Stolte

Senseis Kaz and Beate give the final talk of the sesshin “On Dogen’s Circle of the Way.” Kaz Sensei talks about The Way in various social and historical contexts, explaining that Dogen’s Circle of the Way is always complete, though perhaps imperfect. Sensei Beate speaks of language and the reality it creates as one of myriad possible realities. Beate reads an excerpt by David Foster Wallace about how the clearest parts of our reality are often the most difficult to see and to speak of.

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Big Think Sits Down With Noam Chomsky

Noam Chomsky is always thought-provoking, and sometimes exasperating. Follow the embedded links for Chomsky's views on the various topics mentioned.

Big Think Sits Down With Noam Chomsky

Noam Chomsky, longtime chronicler of the gap between political bombast and legislative boorishness, recently sat down with Big Think to discuss a variety of issues, from his thoughts on Obama, to linguistics, taxes, protesting, love, and the beauty of the “people whose names you’ll never hear.”

When asked to evaluate Obama’s leadership thus far, Chomsky, an avowed anarchist by the age of 12, was unimpressed with any of the president’s current accomplishments. For Chomsky, Obama’s main virtues are in a negative sense—as he has “retracted” some of the more “extreme Bush positions” on issues like nuclear policy or imposed conditions for Cuba . Obama, Chomsky, says, has proven to be exactly what the linguist had imaged and always thought he was, not a beacon of change, but a “familiar center democrat.”

Chomsky also leveled against the president’s treatments of the American workforce and the energy crisis, namely his avoidance of the most necessary and efficacious way to solve the crisis—to actually harness the power of the American workforce as we did during WWII to construct high-speed transit. Currently, “the government and the corporate sector, [are] dismantling the sector of the industrial apparatus, that could very well produce high-speed transit. The automobile industry could be re-tooled for high-speed transit. Much more radical steps have been taken."

After discussing the great unknowables of language, Chomsky, whose wife of 59 years passed away last December, weighed in on the concept of love, describing its “unbreakable grip,” and the hard fact that “life is empty without it.”

I'd have to say agree with his analysis on Obama. There was so much opportunity to do things differently, to make our country better and stronger through a massive public works program to put people back to work and rebuild our infrastructure - and it was all pissed away.

Now he is effing up the whole chance to reform health care.

So far, Obama rates a FAIL, but that is based on my expectations. He has certainly been better than the other option would have been, and his efforts to undo Bush's mess are appreciated.


The Benefits of Religion

Yesterday morning I was being a slacker and not doing homework, so I watched Top Gun, which was on some cable station or another. I really dislike Tom Cruise so I had never seen this flick, but I had heard that it offered a great object lesson in memetics.

Maverick (Cruise's character) is a hot-shot young pilot, but he is very cocky and takes too many risks to show off his skills. Eventually, through no real fault of his own, his best friend and co-pilot dies on a training mission.

Iceman (Val Kilmer) is the rival pilot, equally as talented, but he flies within the rules of the Navy pilots training program, one of which is to never leave your wingman. Iceman eventually wins the Top Gun competition among the pilots in training. Maverick eventually submits to the military structure and saves Iceman in a real life firefight.

Maverick represents an ego-centered memetic stage of development, while Iceman represents a more authoritarian memetic stage. The film demonstrates through (melodrama and bad acting) that the power-drive of the ego needs some strong containment within authority structures to allow it to reach its potential.

By now, you may be wondering what this has to do with the benefits of religion.

Over the weekend, a video made the rounds online of a pastor up in Tempe (just outside of Phoenix) saying he hates Barack Obama and wished him dead. This same man and some of his congregation had shown up at Obama's speech a little more than a week ago armed with assault rifles and handguns.

Here is the video:



This video has resulted in a lot of despair about the role of mythic religion in our culture. You can read some of the discussion the video generated at my friend Stuart's Facebook page.

Many people feel that mythic religion has outlived its usefulness, or that it is no longer an appropriate developmental response to a complex world. This is not wrong, but it is only a partial truth. In fact, the mythic worldview is losing its power, and that is partially why those infected with a more malignant version of this developmental meme are reacting with fear-based violence.

However, not all religion is bad, and not all religion is malignant. As is the case with the military structure portrayed in Top Gun, mythic religion offers a structure to contain the power-drive of the raw ego. But mythic religion is only one form of religion (and here we are talking specifically about Christianity, not Islam, Judaism, or other religions). There are many rational, egalitarian, and even some integral stage Christians. It is not Christianity that is the problem.

The problem, rather, is that some of the people who adhere to a fundamentalist religious dogma also adhere to a very rigid and hateful form of ethnocentrism. The result is a profound fear of the other, and the other is anyone who does not share their specific values and beliefs about the world.

In the example of this clown up in Tempe, the other is Obama - because he is liberal, because he holds some postmodern relativist values (a woman's right to choose what happens to her body), and quite possibly because he is black. The Phoenix metro area is already well-known nationally for its fear/hate of all people who are not them, as Sheriff Joe Arpio demonstrates on a regular basis.

When religion in this country isn't infected with this ethnocentric hatred, it performs valuable roles in society. It has been inner city churches that have done the most to help those involved in the tribal and ego-based power drive of gang culture grow out of that. Even Malcolm X, although his faith was Islam, found containment for his power-drives in the authoritarian structure of religion.

In the same way that sports teams or the military provide that rule-bound structure to contain the raging egos of young men, so does mythic religion. When well-meaning but misguided liberals worked to disempower inner city churches in the sixties and seventies, it was the the neighborhoods that suffered for the lack of religious authority.

And none of this even touches the benefits that religion has for its believers. Churches provide community, comfort, and certainty. While we may not share their values or beliefs, most of these believers are good citizens. The few hateful people should cause us to condemn the whole religion.

It's strange that I find myself, an atheist, defending religion so often against other atheists. This is not the first time, and it likely won't be the last that I make these arguments, so I guess it part of what this blog is about - an integral approach.


Tsoknyi Rinpoche - Compassion's Juice

This great article was the basis for Tricycle's Daily Dharma quote yesterday - but I liked it and wanted to share the whole article.

Compassion's juice

by Tsoknyi Rinpoche

Tsoknyi RInpoche article Tricycle

The true, real view is the indivisible unity of emptiness and compassion. Confusion arises when something seemingly is, but actually isn’t, like mistaking a rope for a snake. That is a clear mistake, because in reality the rope is not a snake, no way.

How do we actualize this view? We have a lot of thoughts, one after the other, involving the duality of subject and object. When the subject latches onto or grasps the object, that is what is normally called mind, the thinking mind. When there is this subject-object clinging, that creates karma. When karma is created, there is confusion.

What is this thinker that always grasps onto an object? That is what we need to discover. What is it, really? Identify what it is that thinks, clearly and directly. It is as simple and immediate as switching on a light. Instead of thinking of this and that, one thing after the other, let your mind recognize itself in a single moment. When the mind recognizes itself, there is no thing to see there. It’s just wide open. That’s because the essence of mind is empty. It’s wide open and free.

This busy, grasping mind,
Always latching onto things,
Let it be given a break to recognize itself instead.
In that very moment of recognition,
This mind becomes wide open,
Free, and unconfined.
That’s called empty essence.

At the same time, there is a certain knowing that it is empty.
That’s called cognizant nature.
Your mind’s empty essence and cognizant nature function simultaneously.
They are not two separate things, not at all.
In fact, they are indivisible.
That’s called unconfined capacity.
Know these three simultaneously -
Empty essence, cognizant nature, and unconfined capacity -
That’s called the view.

In this way, to actualize the view, to realize or understand the view, is to know that our minds are empty in essence and cognizant by nature simultaneously.

Essence is like the sun itself. The sun’s nature is to shine, to be warm, and to illuminate. In the same way, you should distinguish between mind and mind essence. Mind essence has all three of these qualities. It is the essence of this mind essence that is empty, the nature of this mind essence that is cognizant, and the capacity of this mind essence that is unconfined.

The ground is Buddha-nature, which is unmistaken in nature, the basic state of all things. It is the natural state, which is not made by the Buddha, and not created by any ordinary being either. It’s naturally so, all by itself. That is the ultimate truth. Whether a buddha comes into this world or not, the nature of things is still the nature of things. The Buddha is someone who realizes what is true, what actually exists. If we want to become enlightened, we simply have to acknowledge or recognize what is.

What is the basic state, the ground? Through training on the path, we realize the ground as the fruition. We contact what was there to begin with. At the moment, while we are deluded and on the path, we are not seeing it as it is. We are mistaking it for something else, just like mistaking a rope for a snake. We need to abandon that state of temporary confusion.

The path is the state of confusion. To remove it we need view, meditation, and conduct. When we have a glimpse of natural mind, it’s like we see a piece of the ground. The more we get used to it, the more we see, until we finally realize the ground as it is in its entirety.

That’s why, in the context of the path, there are three aspects: recognizing, perfecting the training of that recognition, and attaining stability. We need to dissolve confusion. At the moment of the view, dissolve the confusion. When meditating, dissolve the confusion. When applying the conduct, dissolve the confusion. When all confusion has been totally removed or dissolved, then you can call that fruition.

If we don’t know or experience the indivisibility of emptiness and compassion, it’s hard to get through life smoothly. Imagine a man and woman who live together happily and love each other very deeply. One day the wife hears some teachings, and she becomes interested in the dharma. She listens a lot and understands emptiness; she realizes that nothing in this life has lasting substance. There’s no real core or substance to anything.

Then she thinks, “My husband and I, we go to lots of parties. We go shopping and buy all sorts of things. But actually, none of that really matters to me anymore.” And she starts to close herself up, to shut herself off from her past activities. From one point of view, what she thinks is actually true. Everything is in fact insubstantial, there’s no real point to it. The husband is puzzled and thinks, “My wife is changing. Maybe I did something wrong? Maybe she has a new boyfriend?” But he lets it slide for a while.

Then she starts going into a room, closing the door, and doing prostrations, which he can hear - “boom, boom, boom” - and he thinks, “Hey, my wife is going a little crazy.” Sometimes she sits in a really strange way, holding a string of beads in one hand. The husband thinks, “This is really weird!” So he says, “Tonight, let’s go out and have some fun.” She says, “That doesn’t mean anything to me anymore. I like just sitting here. Besides, why waste the money?”

And he thinks, “Before, she was very active. She’d cook us delicious meals, water the garden, and do all sorts of things. But nowadays she’s doing less and less.”

She thinks, “What’s the use of watering the garden? You have to do it again tomorrow; it’s never enough. What’s the point? I’ll just sit and practice.”

Now the husband’s beginning to get unhappy. They start to growl and argue back and forth. In a while, perhaps, they will separate.

What’s wrong with this woman? She understands emptiness but not compassion. If there were more compassion in her, then she would realize that although certain things may be pointless, it’s not necessary to avoid doing them just because they don’t mean anything for oneself. They may be important to others, so why not just do them? Actually, if the woman truly understood openness and compassion she would be happy to do something meaningless if it made others happy. She would be even more eager to do it than before, when it was merely her own enjoyment she was pursuing! This is the Mahayana style.

Vajrayana is even better, because you can do anything, enjoy anything, without attachment or clinging. The indivisibility of emptiness and compassion means they should be a unity. It’s not enough to just understand emptiness and the general pointlessness of things, because then we may become selfish and apathetic. If we understand emptiness in a one-sided way, thinking “Things are pointless and nothing really matters to me,” then we don’t really care about what matters for others, either. We might end up saying, “I’ll just sit here and meditate because then I’m happy. I don’t care about anything else.”

Compassion without the understanding of emptiness easily becomes selfish attachment, while understanding emptiness without compassion can also become selfish, one-sided, and limited. In order to avoid those dangers, it’s very important to understand the unity of emptiness and compassion. Your naked, present ordinary mind is the door to this unity of compassionate emptiness.

Right now this door is closed by our preoccupation with an almost uninterrupted string of thoughts. But if we allow just one gap between one thought and the next, we may glimpse the naked ordinary mind, self-existing awareness. Then the door is opened right there, to reveal compassion and emptiness united. It is a timeless moment.

The great wisdom qualities of the Buddha-mind - that wisdom that sees the innate nature as it is and the wisdom that perceives all possible things - are blocked again and again, almost continuously, by the concepts that we form. These concepts are actually temporally based; they are, in essence, time. The moment we start to allow gaps in this flow of concepts, the innate qualities of the awakened state begin to shine through.

After fixation on the concept of self dissolves, the expression of that realization manifests as compassion. The true compassion is undirected, and holds no conceptual focus. That kind of genuine, true compassion is only possible after realizing emptiness.

Of course, we feel compassionate right now as well. However, that kind of compassion is not true and genuine compassion, because it’s always mixed with a conceptual frame of mind. Often mixed with our compassion we feel some distance between ourselves and others. “I am here, and sentient beings are over there. I am higher than they are. They are pitiful. They need help, so I should help them.” That is not true compassion either.

Tsoknyi Rinpoche article Tricycle 2

There is clarity of mind, a natural awake quality, from which compassion can arise. It does not center on someone in particular whom we feel sorry for. During this moment there is not a conceptualizing of “another being,” but still in this tenderness there is some way of directing one’s attention to other beings who have not yet recognized the nature of mind. And there is a feeling of sorrow for sentient beings who don’t know that their nature is self-existing wakefulness and therefore are deluded in samsara. This way of reaching out is not really formulated, but we can call it nonconceptual compassion, genuine compassion. That compassion is not necessarily the same as the completely awakened state of a buddha. It is a sign of a yogi on the path, a genuine practitioner.

On the other hand, if we are someone who hasn’t yet recognized the nature of mind, it doesn’t mean that we can’t be genuinely compassionate. There is a way also to be conceptually compassionate, which is different. That is the frame of mind in which we regard ourselves as less important than others. Usually beings regard themselves as more important than others. When we have the attitude that others are more important than me, we call that genuine, although still conceptual, compassion.

What is the experience of true compassion? While recognizing mind essence, there’s some sense of being wide awake and free. At the same time there’s some tenderness that arises without any cause or condition. There is a deep-felt sense of being tender. Not sad in a depressed way, but tender, and somewhat delighted at the same time. There’s a mixture. There’s no sadness for oneself. Nor is there sadness for anyone in particular either. It’s like being saturated with juice, just like an apple is full of juice.

In the same way, the empty openness is saturated with the juice of compassion. Why? Because a lot of qualities are present here. Knowing our empty nature clearly creates an immediate sense of certainty. This certainty has a taste.

There’s a certain time of day, when the sun is setting in the west, when, if we go outside and sit and face the sunset, a feeling of compassion arises easily, spontaneously. It’s kind of free and a little joyful, a little tender, a little sad. It comes all by itself. If you’re not totally open or free from within, then this sadness is not really felt, or even noticed.

If there is any sadness without the openness, notice that it’s always for someone in particular, be it me or him or her. When we simply let ourselves be in that open way, there is a feeling of renunciation, not in the sense of giving up something, but more like letting go of ambition. More like being content.

Imagine a man and woman who live together happily. One day the wife hears some teachings, and she becomes interested in the dharma. She starts going into a room, closing the door, and doing prostrations. The husband hears “boom, boom, boom” and thinks, “Hey, my wife is going a little crazy.”

Compassion without the understanding of emptiness easily becomes selfish attachment, while understanding emptiness without compassion can also become selfish, one-sided, and limited.

After fixation on the concept of self dissolves, the expression of that realization manifests as compassion.

There’s a certain time of day, when the sun is setting in the west, when, if we go outside and face the sunset, a feeling of compassion arises spontaneously. It’s kind of free and a little joyful, a little tender, a little sad. It comes all by itself.

Tsoknyi Rinpoche is a reincarnate lama educated in the Tibetan Buddhist tradition. He has been teaching students since 1990. “Dissolving the Confusion” is adapted from his book Carefree Dignity, reprinted with permission from Rangjung Yeshe Publications.

Image 1: Untitled. Susan Frecon, watercolor on old paper, 1996. Courtesy Lawrence Markey Gallery

Image 2: Sun ("Star Series"), Susan Frecon, watercolor on old paper, 1995. Courtesy Lawrence Markey Gallery


Sunday, August 30, 2009

TED Talks - Alain de Botton: A kinder, gentler philosophy of success

Nice.

Alain de Botton examines our ideas of success and failure -- and questions the assumptions underlying these two judgments. Is success always earned? Is failure? He makes an eloquent, witty case to move beyond snobbery to find true pleasure in our work.

Through his witty and literate books -- and his new School of Life -- Alain de Botton helps others find fulfillment in the everyday. Full bio and more links.






G. Frank Lawlis - Sex and ADD or ADHD

Interesting article from the blogs at Psychology Today.

Redefining Stress

How to train your brain to conquer anxiety and depression

Sex and ADD or ADHD

Sex life with ADD can be good or bad.

The last blog entry I posted related some important issues about the challenges (or advantages) of sex and the nature of the ADD or ADHD brain dynamics. I have been asked some very thought-provoking questions, but I feel I need to address one now: The observation with opposite conclusions. Assuming he/she was a professional and using patients' reports instead of direct observation, the person commented that the individuals worked with reported with reported that they "disassociated" from the activities and dreaded the activity. I don't mind people disagreeing with me, otherwise I would not be in this business, but it worried me that somebody was being misled by information about this field. Since the huge majority of AD(H)D is still being done by a sample of some leading questions instead of anchoring the diagnosis and treatment on objective and functional measurements, there are many readers who read AD(H)D and lack of concentration as the same. Actually those symptoms pertain to about 90 percent of all diagnoses in the DSM-IV.

This response puzzled me and made me wonder what kinds of people he/she was placing the old ADD label on. "Disassociation" in psychological terms usually related to anxiety reactions in which the person escapes into another reality or another personality as a defensive mechanism to a threat. Granted, we have found in our clinic an error rate of 67 percent of misdiagnosis of ADD in which anxiety was found to be the primary cause for inattention and lack of concentration. After all, confusion, inattention and lack of concentration are major symptoms of anxiety, but if you ever observed anyone with high anxiety who was administered one of the stimulants, such as Adderall or Ritalin, you will notice how really panic stricken they get and how destructive those medications can be. The brain signatures are opposite one another. ADD is a sluggish brain (frontal lobe) while anxiety is an over-reactive brain.

So it might make sense that when a person who is easily traumatized he or she might go into a state of disassociation from fear, as in the case of PTSD or trauma. In which case, we are not talking the same language or experience anymore.

On the other hand, as I tried to explain, when a person with the sluggish brain of ADD (ADHD) goes into a state of low energy or enthusiasm, it is probably more a state of boredom or switch in attention. The sex life of this brain signature can be very creative and spontaneous; otherwise, there is the tendency to become interested in something else. For that reason, you should never leave the television set on or e-mail on during this time, especially for those football fans during the Super Bowl play-offs. In fact, you might just want to give up for the whole week.

This tendency brings me to the point of "stimulus-control." The ADD dynamic usually relates to creativity and impulsiveness, but this does not mean that you don't have to plan some of the spontaneity. Things can get out of hand without some control, which is why there are a lot of divorces caused by loss of boundaries, due to "spontaneity." This is not considered lightly because there have been comments regarding this major concern.

But it also means there should be some planning for controlling a person's focus. Usually this is done with smells (flowers and candle), sounds (music and words), kinesthetic cues (touching and holding) and many other factors that can be learned over time.

It can be a life mission.